A preliminary MRI-based study of the brains of individuals with Type I
and Type II bipolar disorder has found physical differences in the
volume of gray and white matter and of cerebrospinal fluid. These
findings seem to be consistent with earlier studies showing a link
between brain volume and depression:
http://www.psmag.com/navigation/health-and-behavior/trip-bipolar-disorder-mental-illness-brains-study-research-mind-95877/
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